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MDMA is a potent central nervous system (CNS) stimulant. The effects include altered sensations, increased energy, empathy, and pleasure. MDMA is currently in clinical trials as a possible treatment aid for post-traumatic stress disorder (PTSD); anxiety in terminally ill patients; and for social anxiety in autistic adults. MDMA increases the activity of three brain chemicals:
Dopamine—produces increased energy/activity and acts in the reward system to reinforce behaviors
Norepinephrine—increases heart rate and blood pressure
Serotonin—affects mood, appetite, sleep, and other functions.
In addition, It also triggers hormones that affect sexual arousal and trust. The release of large amounts of serotonin likely causes the emotional closeness, elevated mood, and empathy felt by those who use MDMA.
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